BDBM50543145 CHEMBL4641604

SMILES Cc1cc(cc2cn(nc12)C1CCNCC1)-c1ccc(=O)n(C)c1C

InChI Key InChIKey=SQHSDIUUVPLPDO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50543145   

TargetToll-like receptor 4(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50543145(CHEMBL4641604)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at TLR4 in human PBMC assessed as inhibition of LPS-induced TNFalpha production preincubated for 30 mins followed by LPS addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed